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National Heart Forum

Victoria House, 7th Floor
Southampton Row
London WC1B 4AD
England

Phone: 020 7831 7420
Fax: 020 3077 5964
Email: [email protected]

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Research directory

This page lists the latest information on peer reviewed chronic disease prevention research. Please note that if you are looking for an item which pre-dates mid-March 2011 you will need to search our archive news and research directory.

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We also provide listings of the latest news information on chronic disease prevention.

Article title
A review of the evidence for the effects of total dietary fat, saturated, monounsaturated and n-6 polyunsaturated fatty acids on vascular function, endothelial progenitor cells and microparticles
Source
British Journal of Nutrition; 107; pg. 303-324;
Date 14 February 2012
Abstract
Aim: Vascular dysfunction is recognised as an integrative marker of CVD. While dietary strategies aimed at reducing CVD risk include reductions in the intake of SFA, there are currently no clear guidelines on what should replace SFA. The purpose of this review was to assess the evidence for the effects of total dietary fat and individual fatty acids (SFA, MUFA and n-6 PUFA) on vascular function, cellular microparticles and endothelial progenitor cells.
Conclusion: The lack of studies with comparable within-study dietary fatty acid targets, a variety of different study designs and different methods for determining vascular function all confound any clear conclusions on the impact of dietary fat and individual fatty acids on vascular function.